Selective endothelin A receptor antagonism with sitaxentan reduces neointimal lesion size in a mouse model of intraluminal injury

BACKGROUND AND PURPOSE: Endothelin (ET) receptor antagonism reduces neointimal lesion formation in animal models. This investigation addressed the hypothesis that the selective ET(A) receptor antagonist sitaxentan would be more effective than mixed ET(A)(/)(B) receptor antagonism at inhibiting neoin...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Duthie, Karolina M, Hadoke, Patrick W F, Kirkby, Nicholas S, Miller, Eileen, Ivy, Jessica R, McShane, John F, Lim, Win Gel, Webb, David J
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4439878/
https://ncbi.nlm.nih.gov/pubmed/25598351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13086
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