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Novel 3′-Processing Integrase Activity Assay by Real-Time PCR for Screening and Identification of HIV-1 Integrase Inhibitors

The 3′-end processing (3′P) of each viral long terminal repeat (LTR) during human immunodeficiency virus type-1 (HIV-1) integration is a vital step in the HIV life cycle. Blocking the 3′P using 3′P inhibitor has recently become an attractive strategy for HIV-1 therapeutic intervention. Recently, we...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Sakkhachornphop, Supachai, Thongkum, Weeraya, Tayapiwatana, Chatchai
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4439469/
https://ncbi.nlm.nih.gov/pubmed/26064960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/853891
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