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Adenosine induces airway hyperresponsiveness through activation of A(3) receptors on mast cells

BACKGROUND: The mechanisms responsible for the development of airway hyperresponsiveness in asthma are poorly understood. Adenosine levels are high in the lungs of patients with asthma, but a role for adenosine in the development of this cardinal feature of asthma has not been previously reported. O...

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Podrobná bibliografie
Vydáno v:J Allergy Clin Immunol
Hlavní autoři: Hua, Xiaoyang, Chason, Kelly D., Fredholm, Bertil B., Deshpande, Deepak A., Penn, Raymond B., Tilley, Stephen L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4439463/
https://ncbi.nlm.nih.gov/pubmed/18472152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2008.03.026
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