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Cell Clustering and Delay/Arrest in T-Cell Division Implicate A Novel Mechanism of Immune Modulation by E. coli Heat-Labile Enterotoxin B-Subunits
The B-subunits of heat-labile enterotoxins LT-I (LT-IB) and LT-IIa (LT-IIaB) are strong adjuvants that bind to cell-surface receptors, including gangliosides G(M1) and GD1b, respectively. LT-IIaB also binds TLR-2. We demonstrate for the first time that co-incubation with the B-subunits induces signi...
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| Published in: | Cell Immunol |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4439354/ https://ncbi.nlm.nih.gov/pubmed/25880107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2015.02.014 |
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