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The Preclinical Alzheimer Cognitive Composite: Measuring Amyloid-Related Decline

IMPORTANCE: As Alzheimer disease (AD) research moves to intervene in presymptomatic phases of the disease, we must develop outcome measures sensitive to the earliest disease-related changes. OBJECTIVE: To demonstrate the feasibility of a cognitive composite outcome for clinically normal elderly part...

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Detalhes bibliográficos
Publicado no:JAMA Neurol
Main Authors: Donohue, Michael C., Sperling, Reisa A., Salmon, David P., Rentz, Dorene M., Raman, Rema, Thomas, Ronald G., Weiner, Michael, Aisen, Paul S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4439182/
https://ncbi.nlm.nih.gov/pubmed/24886908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2014.803
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