Catalase Therapy Corrects Oxidative Stress-Induced Pathophysiology in Incipient Diabetic Retinopathy

PURPOSE. Preclinical studies have highlighted retinal oxidative stress in the pathogenesis of diabetic retinopathy. We evaluated whether a treatment designed to enhance cellular catalase reduces oxidative stress in retinal cells cultured in high glucose and in diabetic mice corrects an imaging bioma...

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Dades bibliogràfiques
Publicat a:Invest Ophthalmol Vis Sci
Autors principals: Giordano, Courtney R., Roberts, Robin, Krentz, Kendra A., Bissig, David, Talreja, Deepa, Kumar, Ashok, Terlecky, Stanley R., Berkowitz, Bruce A.
Format: Artigo
Idioma:Inglês
Publicat: The Association for Research in Vision and Ophthalmology 2015
Matèries:
Retina
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4439131/
https://ncbi.nlm.nih.gov/pubmed/25813998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-16194
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