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Generation of a safe and effective live viral vaccine by virus self-attenuation using species-specific artificial microRNA
Vaccination with live attenuated vaccines (LAVs) is an effective way for prevention of infectious disease. While several methods are employed to create them, efficacy and safety are still a challenge. In this study, we evaluated the feasibility of creating a self-attenuated RNA virus expressing a fu...
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| Publicado no: | J Control Release |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4439010/ https://ncbi.nlm.nih.gov/pubmed/25858415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2015.04.001 |
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