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Nanoscale protein domain motion and long-range allostery in signaling proteins—a view from neutron spin echo spectroscopy

Many cellular proteins are multi-domain proteins. Coupled domain–domain interactions in these multidomain proteins are important for the allosteric relay of signals in the cellular signaling networks. We have initiated the application of neutron spin echo spectroscopy to the study of nanoscale prote...

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Bibliografiske detaljer
Udgivet i:Biophys Rev
Main Authors: Callaway, David J. E., Bu, Zimei
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4438997/
https://ncbi.nlm.nih.gov/pubmed/26005503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12551-015-0162-x
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