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Calcitriol ameliorates renal damage in a pre-established proteinuria model
Proteinuria is critical in the tubulointerstitial changes that ultimately lead to renal insufficiency. Increased protein filtration has direct toxic effects on tubular epithelial cells, leading to epithelial mesenchymal transition (EMT) to a myofibroblast phenotype. Angiotensin II and transforming g...
Gespeichert in:
| Veröffentlicht in: | Mol Med Rep |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
D.A. Spandidos
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4438961/ https://ncbi.nlm.nih.gov/pubmed/25823676 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2015.3555 |
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