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Fully human HER2/cluster of differentiation 3 bispecific antibody triggers potent and specific cytotoxicity of T lymphocytes against breast cancer

The use of a bispecific antibody (BsAb) is a promising and highly specific approach to cancer therapy. In the present study, a fully human recombinant single chain variable fragment BsAb against human epidermal growth factor receptor (HER)2 and cluster of differentiation (CD)3 was constructed with t...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: ZHOU, YAN, GOU, LAN-TU, GUO, ZHI-HUI, LIU, HAI-RONG, WANG, JIANG-MAN, ZHOU, SHU-XIAN, YANG, JIN-LIANG, LI, XIAO-AN
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4438947/
https://ncbi.nlm.nih.gov/pubmed/25760691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2015.3441
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