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Cell-to-cell contact facilitates HIV transmission from lymphocytes to astrocytes via CXCR4

OBJECTIVES: HIV reservoir in the brain represents a major barrier for curing HIV infection. As the most abundant, long-lived cell type, astrocytes play a critical role in maintaining the reservoir; however the mechanism of infection remains unknown. Here, we determine how viral transmission occurs f...

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Detalhes bibliográficos
Publicado no:AIDS
Main Authors: Li, Guan-Han, Anderson, Caroline, Jaeger, Laura, Do, Thao, Major, Eugene O., Nath, Avindra
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4438861/
https://ncbi.nlm.nih.gov/pubmed/25985398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000000605
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