Transient Blockade of ERK Phosphorylation in the Critical Period Causes Autistic Phenotypes as an Adult in Mice

The critical period is a distinct time-window during the neonatal stage when animals display elevated sensitivity to certain environmental stimuli, and particular experiences can have profound and long-lasting effects on behaviors. Increasing evidence suggests that disruption of neuronal activity du...

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Publicado en:Sci Rep
Autores principales: Yufune, Shinya, Satoh, Yasushi, Takamatsu, Isao, Ohta, Hiroyuki, Kobayashi, Yasushi, Takaenoki, Yumiko, Pagès, Gilles, Pouysségur, Jacques, Endo, Shogo, Kazama, Tomiei
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4438718/
https://ncbi.nlm.nih.gov/pubmed/25993696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10252
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