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Key role of hepatitis B virus mutation in chronic hepatitis B development to hepatocellular carcinoma

Chronic hepatitis B virus (HBV) infection is a major risk factor for hepatocellular carcinoma (HCC). The HBV mutations, which include point mutation, deletion, insertion and truncation mutation of HBV gene in 4 open reading frames (S, C, P, X), are closely associated with HCC pathogenesis. Some muta...

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Bibliografiske detaljer
Udgivet i:World J Hepatol
Main Authors: Zhang, Xin, Ding, Hui-Guo
Format: Artigo
Sprog:Inglês
Udgivet: Baishideng Publishing Group Inc 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4438503/
https://ncbi.nlm.nih.gov/pubmed/26019744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4254/wjh.v7.i9.1282
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