Physical association of JAK1 and JAK2 tyrosine kinases with the interleukin 2 receptor beta and gamma chains.

The functional interleukin 2 (IL-2) receptors contain the beta and gamma chains which are necessary for the transduction of cell growth signals. Monoclonal antibodies specific for the beta chain and gamma chain coimmunoprecipitated JAK1 and 114-kDa JAK2 tyrosine kinases, respectively. Tyrosine phosp...

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Main Authors: Tanaka, N, Asao, H, Ohbo, K, Ishii, N, Takeshita, T, Nakamura, M, Sasaki, H, Sugamura, K
Formato: Artigo
Idioma:Inglês
Publicado: 1994
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC44381/
https://ncbi.nlm.nih.gov/pubmed/8041779
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