Evaluation of Changes in Morphology and Function of Human Induced Pluripotent Stem Cell Derived Cardiomyocytes (HiPSC-CMs) Cultured on an Aligned-Nanofiber Cardiac Patch

INTRODUCTION: Dilated cardiomyopathy is a major cause of progressive heart failure. Utilization of stem cell therapy offers a potential means of regenerating viable cardiac tissue. However, a major obstacle to stem cell therapy is the delivery and survival of implanted stem cells in the ischemic hea...

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Udgivet i:PLoS One
Main Authors: Khan, Mahmood, Xu, Yanyi, Hua, Serena, Johnson, Jed, Belevych, Andriy, Janssen, Paul M. L., Gyorke, Sandor, Guan, Jianjun, Angelos, Mark G.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437999/
https://ncbi.nlm.nih.gov/pubmed/25993466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126338
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