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Optical Imaging of Targeted β-Galactosidase in Brain Tumors to Detect EGFR Levels

A current limitation in molecular imaging is that it often requires genetic manipulation of cancer cells for noninvasive imaging. Other methods to detect tumor cells in vivo using exogenously delivered and functionally active reporters, such as β-gal, are required. We report the development of a pla...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Bioconjug Chem
Hauptverfasser: Broome, Ann-Marie, Ramamurthy, Gopal, Lavik, Kari, Liggett, Alexander, Kinstlinger, Ian, Basilion, James
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437618/
https://ncbi.nlm.nih.gov/pubmed/25775241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc500597y
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