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Tubulation by amphiphysin requires concentration-dependent switching from wedging to scaffolding

BAR proteins are involved in a variety of membrane remodeling events, but how they can mold membranes into different shapes remains poorly understood. Using EPR, we find that vesicle binding of the N-BAR protein amphiphysin is predominantly mediated by the shallow insertion of amphipathic N-terminal...

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Detalhes bibliográficos
Publicado no:Structure
Main Authors: Isas, J. Mario, Ambroso, Mark R., Hegde, Prabhavati B., Langen, Jennifer, Langen, Ralf
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437528/
https://ncbi.nlm.nih.gov/pubmed/25865245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2015.02.014
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