Elimination of Tumorigenic Human Pluripotent Stem Cells by a Recombinant Lectin-Toxin Fusion Protein

The application of stem-cell-based therapies in regenerative medicine is hindered by the tumorigenic potential of residual human pluripotent stem cells. Previously, we identified a human pluripotent stem-cell-specific lectin probe, called rBC2LCN, by comprehensive glycome analysis using high-density...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Tateno, Hiroaki, Onuma, Yasuko, Ito, Yuzuru, Minoshima, Fumi, Saito, Sayoko, Shimizu, Madoka, Aiki, Yasuhiko, Asashima, Makoto, Hirabayashi, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437484/
https://ncbi.nlm.nih.gov/pubmed/25866158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.02.016
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