Valproic Acid Neuroprotection in the 6-OHDA Model of Parkinson's Disease Is Possibly Related to Its Anti-Inflammatory and HDAC Inhibitory Properties

Parkinson's disease is a neurodegenerative disorder where the main hallmark is the dopaminergic neuronal loss. Besides motor symptoms, PD also causes cognitive decline. Although current therapies focus on the restoration of dopamine levels in the striatum, prevention or disease-modifying therap...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Neurodegener Dis
Main Authors: Ximenes, José Christian Machado, Neves, Kelly Rose Tavares, Leal, Luzia Kalyne A. M., do Carmo, Marta Regina Santos, Brito, Gerly Anne de Castro, Naffah-Mazzacoratti, Maria da Graça, Cavalheiro, Ésper Abrão, Viana, Glauce Socorro de Barros
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2015
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437346/
https://ncbi.nlm.nih.gov/pubmed/26317011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/313702
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