Glial Cell Line-Derived Neurotrophic Factor Family Members Reduce Microglial Activation via Inhibiting p38MAPKs-Mediated Inflammatory Responses

Previous studies have shown that glial cell line-derived neurotrophic factor (GDNF) family ligands (GFL) are potent survival factors for dopaminergic neurons and motoneurons with therapeutic potential for Parkinson's disease. However, little is known about direct influences of the GFL on microg...

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Détails bibliographiques
Publié dans:J Neurodegener Dis
Auteurs principaux: Rickert, Uta, Grampp, Steffen, Wilms, Henrik, Spreu, Jessica, Knerlich-Lukoschus, Friederike, Held-Feindt, Janka, Lucius, Ralph
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2014
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437344/
https://ncbi.nlm.nih.gov/pubmed/26317008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/369468
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