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Triplex real-time PCR–an improved method to detect a wide spectrum of mitochondrial DNA deletions in single cells
Mitochondrial DNA (mtDNA) mutations are commonly found in the skeletal muscle of patients with mitochondrial disease, inflammatory myopathies and sarcopenia. The majority of these mutations are mtDNA deletions, which accumulate to high levels in individual muscle fibres causing a respiratory defect....
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| Опубликовано в: : | Sci Rep |
|---|---|
| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4437295/ https://ncbi.nlm.nih.gov/pubmed/25989140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09906 |
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