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Triplex real-time PCR–an improved method to detect a wide spectrum of mitochondrial DNA deletions in single cells
Mitochondrial DNA (mtDNA) mutations are commonly found in the skeletal muscle of patients with mitochondrial disease, inflammatory myopathies and sarcopenia. The majority of these mutations are mtDNA deletions, which accumulate to high levels in individual muscle fibres causing a respiratory defect....
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4437295/ https://ncbi.nlm.nih.gov/pubmed/25989140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09906 |
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