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Structure of Slitrk2–PTPδ complex reveals mechanisms for splicing-dependent trans-synaptic adhesion

Selective binding between pre- and postsynaptic adhesion molecules can induce synaptic differentiation. Here we report the crystal structure of a synaptogenic trans-synaptic adhesion complex between Slit and Trk-like family member 2 (Slitrk2) and receptor protein tyrosine phosphatase (RPTP) δ. The s...

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Vydáno v:Sci Rep
Hlavní autoři: Yamagata, Atsushi, Sato, Yusuke, Goto-Ito, Sakurako, Uemura, Takeshi, Maeda, Asami, Shiroshima, Tomoko, Yoshida, Tomoyuki, Fukai, Shuya
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437028/
https://ncbi.nlm.nih.gov/pubmed/25989451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09686
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