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Upregulation of bile acid receptor TGR5 and nNOS in gastric myenteric plexus is responsible for delayed gastric emptying after chronic high-fat feeding in rats

Chronic high-fat feeding is associated with functional dyspepsia and delayed gastric emptying. We hypothesize that high-fat feeding upregulates gastric neuronal nitric oxide synthase (nNOS) expression, resulting in delayed gastric emptying. We propose this is mediated by increased bile acid action o...

詳細記述

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書誌詳細
出版年:Am J Physiol Gastrointest Liver Physiol
主要な著者: Zhou, Hui, Zhou, Shiyi, Gao, Jun, Zhang, Guanpo, Lu, Yuanxu, Owyang, Chung
フォーマット: Artigo
言語:Inglês
出版事項: American Physiological Society 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437020/
https://ncbi.nlm.nih.gov/pubmed/25540233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00380.2014
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