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Promise and challenges on the horizon of MET-targeted cancer therapeutics
MET (MNNG HOS transforming gene) is one of the receptor tyrosine kinases whose activities are frequently altered in human cancers, and it is a promising therapeutic target. MET is normally activated by its lone ligand, hepatocyte growth factor (HGF), eliciting its diverse biological activities that...
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| Publicado en: | World J Biol Chem |
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| Autor principal: | |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Baishideng Publishing Group Inc
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4436902/ https://ncbi.nlm.nih.gov/pubmed/26009700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4331/wjbc.v6.i2.16 |
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