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Promise and challenges on the horizon of MET-targeted cancer therapeutics

MET (MNNG HOS transforming gene) is one of the receptor tyrosine kinases whose activities are frequently altered in human cancers, and it is a promising therapeutic target. MET is normally activated by its lone ligand, hepatocyte growth factor (HGF), eliciting its diverse biological activities that...

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Detalhes bibliográficos
Publicado no:World J Biol Chem
Autor principal: Zhang, Yu-Wen
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4436902/
https://ncbi.nlm.nih.gov/pubmed/26009700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4331/wjbc.v6.i2.16
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