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KAR3-encoded kinesin is a minus-end-directed motor that functions with centromere binding proteins (CBF3) on an in vitro yeast kinetochore.

We have used in vitro motility assays to investigate the mechanism of kinetochore function in the budding yeast Saccharomyces cerevisiae. Functional centromeric DNA plus a tripartite centromere binding protein complex, CBF3, was found to be necessary but not sufficient for in vitro kinetochore activ...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Middleton, K, Carbon, J
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1994
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44369/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8041770/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.15.7212
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