Role of nuclear receptor CAR in carbon tetrachloride-induced hepatotoxicity

AIM: To investigate the precise roles of CAR in CCl(4)-induced acute hepatotoxicity. METHODS: To prepare an acute liver injury model, CCl(4)- induced was intraperitoneally injected in CAR(+/+) and CAR(-/-) mice. RESULTS: Elevation of serum alanine aminotransferase and extension of centrilobular necr...

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Bibliografiske detaljer
Udgivet i:World J Gastroenterol
Main Authors: Yamazaki, Yuichi, Kakizaki, Satoru, Horiguchi, Norio, Takagi, Hitoshi, Mori, Masatomo, Negishi, Masahiko
Format: Artigo
Sprog:Inglês
Udgivet: Baishideng Publishing Group Inc 2005
Fag:
Basic Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4436718/
https://ncbi.nlm.nih.gov/pubmed/16273607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v11.i38.5966
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