HIM-8 Binds to the X Chromosome Pairing Center and Mediates Chromosome-Specific Meiotic Synapsis

The him-8 gene is essential for proper meiotic segregation of the X chromosomes in C. elegans. Here we show that loss of him-8 function causes profound X chromosome-specific defects in homolog pairing and synapsis. him-8 encodes a C2H2 zinc-finger protein that is expressed during meiosis and concent...

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Udgivet i:Cell
Main Authors: Phillips, Carolyn M., Wong, Chihunt, Bhalla, Needhi, Carlton, Peter M., Weiser, Pinky, Meneely, Philip M., Dernburg, Abby F.
Format: Artigo
Sprog:Inglês
Udgivet: 2005
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4435792/
https://ncbi.nlm.nih.gov/pubmed/16360035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2005.09.035
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