Effect of Adjuvant Capecitabine or Fluorouracil, with or without Oxaliplatin, on Survival Outcomes in Stage III Colon Cancer and the Effect of Oxaliplatin on Post-Relapse Survival: A Pooled Analysis of Individual Patient Data from Four Randomised Controlled Trials

BACKGROUND: Oxaliplatin-based adjuvant therapy is the standard of care for stage III colon cancer. Adjuvant capecitabine with or without oxaliplatin versus leucovorin and fluorouracil with or without oxaliplatin has not been directly compared; therefore, we aimed to analyse the efficacy and safety o...

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Pubblicato in:Lancet Oncol
Autori principali: Schmoll, Hans-Joachim, Twelves, Chris, Sun, Weijing, O'Connell, Michael J, Cartwright, Thomas, McKenna, Edward, Saif, Muhammad, Lee, Steve, Yothers, Greg, Haller, Daniel
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4435787/
https://ncbi.nlm.nih.gov/pubmed/25456367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1470-2045(14)70486-3
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