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ID Proteins Regulate Diverse Aspects of Cancer Progression and Provide Novel Therapeutic Opportunities

The inhibitor of differentiation (ID) proteins are helix-loop-helix transcriptional repressors with established roles in stem cell self-renewal, lineage commitment, and niche interactions. While deregulated expression of ID proteins in cancer was identified more than a decade ago, emerging evidence...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Nair, Radhika, Teo, Wee Siang, Mittal, Vivek, Swarbrick, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4435600/
https://ncbi.nlm.nih.gov/pubmed/24827908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.83
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