Blockade of ActRIIB Signaling Triggers Muscle Fatigability and Metabolic Myopathy

Myostatin regulates skeletal muscle size via the activin receptor IIB (ActRIIB). However, its effect on muscle energy metabolism and energy-dependent muscle function remains largely unexplored. This question needs to be solved urgently since various therapies for neuromuscular diseases based on bloc...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Ther
Main Authors: Relizani, Karima, Mouisel, Etienne, Giannesini, Benoit, Hourdé, Christophe, Patel, Ketan, Morales Gonzalez, Susanne, Jülich, Kristina, Vignaud, Alban, Piétri-Rouxel, France, Fortin, Dominique, Garcia, Luis, Blot, Stéphane, Ritvos, Olli, Bendahan, David, Ferry, Arnaud, Ventura-Clapier, Renée, Schuelke, Markus, Amthor, Helge
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2014
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4435590/
https://ncbi.nlm.nih.gov/pubmed/24861054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.90
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