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Elimination of background recombination: somatic induction of Cre by combined transcriptional regulation and hormone binding affinity
Somatically inducible Cre lines are used extensively to study gene function. However, a background level of spontaneous recombination due to unregulated expression of Cre is particularly confounding for cancer models in which following the pathogenesis of the disease requires the introduction of spo...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC443557/ https://ncbi.nlm.nih.gov/pubmed/15247325 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gnh090 |
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