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Elimination of background recombination: somatic induction of Cre by combined transcriptional regulation and hormone binding affinity
Somatically inducible Cre lines are used extensively to study gene function. However, a background level of spontaneous recombination due to unregulated expression of Cre is particularly confounding for cancer models in which following the pathogenesis of the disease requires the introduction of spo...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , , |
|---|---|
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Oxford University Press
2004
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC443557/ https://ncbi.nlm.nih.gov/pubmed/15247325 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gnh090 |
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