pH-sensitive poly(lactide-co-glycolide) nanoparticle composite microcapsules for oral delivery of insulin

This study proposes a new concept of pH-sensitive poly(lactide-co-glycolide) (PLGA) nanoparticle composite microcapsules for oral delivery of insulin. Firstly, insulin–sodium oleate complex was prepared by the hydrophobic ion pairing method and then encapsulated into PLGA nanoparticles by the emulsi...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Sun, Shaoping, Liang, Na, Yamamoto, Hiromitsu, Kawashima, Yoshiaki, Cui, Fude, Yan, Pengfei
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4435433/
https://ncbi.nlm.nih.gov/pubmed/25999713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S81715
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