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DNA sequence recognition by an isopropyl substituted thiazole polyamide
We have used DNA footprinting and fluorescence melting experiments to study the sequence-specific binding of a novel minor groove binding ligand (thiazotropsin A), containing an isopropyl substituted thiazole polyamide, to DNA. In one fragment, which contains every tetranucleotide sequence, sub-micr...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2004
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC443542/ https://ncbi.nlm.nih.gov/pubmed/15247333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh666 |
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