Inhibition of Follicle-Stimulating Hormone-Induced Preovulatory Follicles in Rats Treated with a Nonsteroidal Negative Allosteric Modulator of Follicle-Stimulating Hormone Receptor

We previously described a negative allosteric modulator (NAM) of FSHR (ADX61623) that blocked FSH-induced cAMP and progesterone production but did not block estradiol production. That FSHR NAM did not affect FSH-induced preovulatory follicle development as evidenced by the lack of an effect on the n...

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Detalles Bibliográficos
Publicado en:Biol Reprod
Main Authors: Dias, James A., Campo, Brice, Weaver, Barbara A., Watts, Julie, Kluetzman, Kerri, Thomas, Richard M., Bonnet, Béatrice, Mutel, Vincent, Poli, Sonia M.
Formato: Artigo
Idioma:Inglês
Publicado: Society for the Study of Reproduction, Inc. 2013
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4435417/
https://ncbi.nlm.nih.gov/pubmed/24285717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.113.109397
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