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Cryptorchidism in the Orl Rat Is Associated with Muscle Patterning Defects in the Fetal Gubernaculum and Altered Hormonal Signaling

Cryptorchidism, or undescended testis, is a common male genital anomaly of unclear etiology. Hormonal stimulation of the developing fetal gubernaculum by testicular androgens and insulin-like 3 (INSL3) is required for testicular descent. In studies of the orl fetal rat, one of several reported strai...

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Detalles Bibliográficos
Publicado en:Biol Reprod
Main Authors: Barthold, Julia S., Robbins, Alan, Wang, Yanping, Pugarelli, Joan, Mateson, Abigail, Anand-Ivell, Ravinder, Ivell, Richard, McCahan, Suzanne M., Akins, Robert E.
Formato: Artigo
Idioma:Inglês
Publicado: Society for the Study of Reproduction, Inc. 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4435416/
https://ncbi.nlm.nih.gov/pubmed/24966393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.114.119560
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