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Nanofabrication of methylglyoxal with chitosan biopolymer: a potential tool for enhancement of its anticancer effect

PURPOSE: The normal metabolite methylglyoxal (MG) specifically kills cancer cells by inhibiting glycolysis and mitochondrial respiration without much adverse effect upon normal cells. Though the anticancer property of MG is well documented, its gradual enzymatic degradation in vivo has prompted inte...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Pal, Aparajita, Talukdar, Dipa, Roy, Anirban, Ray, Subhankar, Mallick, Asish, Mandal, Chitra, Ray, Manju
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4435252/
https://ncbi.nlm.nih.gov/pubmed/25999714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S78284
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