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Development of a Microfluidic-Based Optical Sensing Device for Label-Free Detection of Circulating Tumor Cells (CTCs) Through Their Lactic Acid Metabolism

This study reports a microfluidic-based optical sensing device for label-free detection of circulating tumor cells (CTCs), a rare cell species in blood circulation. Based on the metabolic features of cancer cells, live CTCs can be quantified indirectly through their lactic acid production. Compared...

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Detalhes bibliográficos
Publicado no:Sensors (Basel)
Main Authors: Chiu, Tzu-Keng, Lei, Kin-Fong, Hsieh, Chia-Hsun, Hsiao, Hung-Bo, Wang, Hung-Ming, Wu, Min-Hsien
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4435186/
https://ncbi.nlm.nih.gov/pubmed/25808775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/s150306789
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