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Influence of cancer cachexia on drug liver metabolism and renal elimination in rats
BACKGROUND: Body wasting and cachexia change body composition and organ function, with effects on drug pharmacokinetics. The aim of this study was to investigate how cancer and cancer cachexia modify liver metabolism and renal drug elimination in rats. METHODS: Nine male Wistar-Han rats received a s...
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Publicado no: | J Cachexia Sarcopenia Muscle |
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Main Authors: | , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BlackWell Publishing Ltd
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4435096/ https://ncbi.nlm.nih.gov/pubmed/26136411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcsm.12012 |
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