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Pleiotropic Role of HSF1 in Neoplastic Transformation
HSF1 (Heat Shock transcription Factor 1) is the main transcription factor activated in response to proteotoxic stress. Once activated, it induces an expression of heat shock proteins (HSPs) which enables cells to survive in suboptimal conditions. HSF1 could be also activated by altered kinase signal...
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| Publicado no: | Curr Cancer Drug Targets |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Bentham Science Publishers
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4435066/ https://ncbi.nlm.nih.gov/pubmed/24467529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1568009614666140122155942 |
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