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Licochalcone A-induced human gastric cancer BGC-823 cells apoptosis by regulating ROS-mediated MAPKs and PI3K/AKT signaling pathways

Both phosphatidylinositol 3-kinase (PI3K)/AKT and mitogen activated protein kinase (MAPK) signaling cascades play an important role in cell proliferation, survival, angiogenesis, and metastasis of tumor cells. In the present report, we investigated the effects of licochalcone A (LA), a flavonoid ext...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hao, Wenjin, Yuan, Xuan, Yu, Lina, Gao, Caixia, Sun, Xiling, Wang, Dong, Zheng, Qiusheng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4434846/
https://ncbi.nlm.nih.gov/pubmed/25981581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10336
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