Localized SCF and IGF-1 secretion enhances erythropoiesis in the spleen of murine embryos

Fetal spleen is a major hematopoietic site prior to initiation of bone marrow hematopoiesis. Morphologic analysis suggested erythropoietic activity in fetal spleen, but it remained unclear how erythropoiesis was regulated. To address this question, we performed flow cytometric analysis and observed...

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Bibliografiske detaljer
Udgivet i:Biol Open
Main Authors: Tan, Keai Sinn, Inoue, Tomoko, Kulkeaw, Kasem, Tanaka, Yuka, Lai, Mei I, Sugiyama, Daisuke
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4434811/
https://ncbi.nlm.nih.gov/pubmed/25887124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.201410686
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