A ΩXaV motif in the Rift Valley fever virus NSs protein is essential for degrading p62, forming nuclear filaments and virulence

Rift Valley fever virus (RVFV) is a single-stranded RNA virus capable of inducing fatal hemorrhagic fever in humans. A key component of RVFV virulence is its ability to form nuclear filaments through interactions between the viral nonstructural protein NSs and the host general transcription factor T...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Cyr, Normand, de la Fuente, Cynthia, Lecoq, Lauriane, Guendel, Irene, Chabot, Philippe R., Kehn-Hall, Kylene, Omichinski, James G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4434773/
https://ncbi.nlm.nih.gov/pubmed/25918396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1503688112
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