A site of varicella-zoster virus vulnerability identified by structural studies of neutralizing antibodies bound to the glycoprotein complex gHgL

Varicella-zoster virus (VZV), of the family Alphaherpesvirinae, causes varicella in children and young adults, potentially leading to herpes zoster later in life on reactivation from latency. The conserved herpesvirus glycoprotein gB and the heterodimer gHgL mediate virion envelope fusion with cell...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Xing, Yi, Oliver, Stefan L., Nguyen, TuongVi, Ciferri, Claudio, Nandi, Avishek, Hickman, Julie, Giovani, Cinzia, Yang, Edward, Palladino, Giuseppe, Grose, Charles, Uematsu, Yasushi, Lilja, Anders E., Arvin, Ann M., Carfí, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4434712/
https://ncbi.nlm.nih.gov/pubmed/25918416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1501176112
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