Multiple stiffening effects of nanoscale knobs on human red blood cells infected with Plasmodium falciparum malaria parasite

During its asexual development within the red blood cell (RBC), Plasmodium falciparum (Pf), the most virulent human malaria parasite, exports proteins that modify the host RBC membrane. The attendant increase in cell stiffness and cytoadherence leads to sequestration of infected RBCs in microvascula...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Zhang, Yao, Huang, Changjin, Kim, Sangtae, Golkaram, Mahdi, Dixon, Matthew W. A., Tilley, Leann, Li, Ju, Zhang, Sulin, Suresh, Subra
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2015
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4434686/
https://ncbi.nlm.nih.gov/pubmed/25918423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1505584112
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