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When being a bystander is not so innocent
A new mechanism to explain massive depletion of CD4(+) T cells in HIV-1 infection despite the low frequency of productively infected cells involves innate immune sensing of HIV 1 by abortively infected “bystander” CD4(+) T cells. The result is death of the bystander cells through an inflammatory pro...
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| Publicado en: | Nature |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4434588/ https://ncbi.nlm.nih.gov/pubmed/24451540 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/505492a |
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