Impact of Population Stratification on Family-Based Association in an Admixed Population

Population substructure is a well-known confounder in population-based case-control genetic studies, but its impact in family-based studies is unclear. We performed population substructure analysis using extended families of admixed population to evaluate power and Type I error in an association stu...

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Detalles Bibliográficos
Publicado en:Int J Genomics
Autores principales: Mersha, T. B., Ding, L., He, H., Alexander, E. S., Zhang, X., Kurowski, B. G., Pilipenko, V., Kottyan, L., Martin, L. J., Fardo, D. W.
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4434195/
https://ncbi.nlm.nih.gov/pubmed/26064873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/501617
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