Local secretion of corticotropin-releasing hormone in the joints of Lewis rats with inflammatory arthritis.

Corticotropin-releasing hormone (CRH), the principal regulator of the hypothalamic-pituitary-adrenal axis, is also secreted in peripheral inflammatory sites, where it acts as a local proinflammatory agent. Arthritis-susceptible LEW/N rats have profoundly deficient hypothalamic CRH responses to infla...

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Main Authors: Crofford, L J, Sano, H, Karalis, K, Webster, E L, Goldmuntz, E A, Chrousos, G P, Wilder, R L
Formato: Artigo
Idioma:Inglês
Publicado: 1992
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC443415/
https://ncbi.nlm.nih.gov/pubmed/1281840
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