Cytoskeleton-dependent endocytosis is required for apical type 1 angiotensin II receptor-mediated phospholipase C activation in cultured rat proximal tubule cells.

Renal proximal tubule sodium reabsorption is enhanced by apical or basolateral angiotensin II (AII). Although AII activates phospholipase C (PLC) in other tissues, AII coupling to PLC on either apical or basolateral surfaces of proximal tubule cells is unclear. To determine if AII causes PLC activat...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Schelling, J R, Hanson, A S, Marzec, R, Linas, S L
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1992
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443404/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1334976/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116139
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