Pleiotropic effects of antithrombin strand 1C substitution mutations.

Six different substitution mutations were identified in four different amino acid residues of antithrombin strand 1C and the polypeptide leading into strand 4B (F402S, F402C, F402L, A404T, N405K, and P407T), and are responsible for functional antithrombin deficiency in seven independently ascertaine...

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Autores principales: Lane, D A, Olds, R J, Conard, J, Boisclair, M, Bock, S C, Hultin, M, Abildgaard, U, Ireland, H, Thompson, E, Sas, G
Formato: Artigo
Lenguaje:Inglês
Publicado: 1992
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC443398/
https://ncbi.nlm.nih.gov/pubmed/1469094
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